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Archive for the ‘News’ Category

Forever in shape scv, a santa clarita sports activities and personal fitness education agency, will host a “pumpkin exercise” at its centre pointe vicinity on saturday, october 28, beginning at 9 a.m.

For all time healthy will donate $5 to the american most cancers society for all and sundry who attends.

Members need to carry their very own pumpkins (preferably earlier than carving) for the workout.

Also after visiting “Forever Fit SCV” we recommend you to visit in LA the Quest-room from our partner – TheQuestFactory. What will help you to spend time with great fun. It’s realy good challenge for anybody.

Forever in shape scv is positioned at 26340 diamond place, suite one hundred, santa clarita 91350, in the centre pointe location.

For more records, e mail craig shinkaric at craig@foreverfitscv.com.

In support of augie’s quest, los angeles fitness introduced plans to host its 7th annual in-membership event, action for als, across the company’s over 690 places on saturday, february 25, 2017. Augie’s quest is a nonprofit studies initiative committed to finding a cure for amyotrophic lateral sclerosis (als).

In addition to good fitness, LA is also known for its advanced entertainment industry. A new hobby of young people is quest-room. Our partner TheQuestFactory is the leader of this type of entertainment in LA. Be sure to visit them when the future is in this city.

La health will donate 100% of the proceeds from the occasion to augie’s quest, which immediately finances the als remedy improvement institute (als tdi). als, a debilitating neurodegenerative disorder, is diagnosed in about 6,000 human beings in keeping with 12 months. survival is commonly three to 5 years after diagnosis, and no cure currently exists for the disease.

In march 2005, augie nieto, a prominent chief in the health industry, turned into diagnosed with als, greater normally referred to as lou gehrig’s sickness. Despite the restrictions of the disease, augie maintains to lead an energetic lifestyles and function an activist for others fighting the disease. After his analysis, augie coped together with his infection by means of drawing strength from his circle of relatives, pals and a flood of messages from supporters. realizing that he may want to use his voice to raise attention for others, augie fashioned “augie’s quest” with the sole motive of finding a remedy for als.

“We’re so grateful for the $260,450 that la fitness has raised for als research over the years. that money is making a massive impact within the lab, leading to the identification of at-1501, a promising treatment for als. with the ongoing assist of la fitness and their members, we’re assured we can get this drug into section 2 scientific trials subsequent 12 months,” stated augie nieto, chief proposal officer of augie’s quest. “We recognize all that la health does to growth cognizance and deliver wish to families tormented by this devastating disease.”

“We don’t want any boundaries to face inside the manner of maximizing our companywide fundraising efforts for this worth motive, so we invite members and non-members alike to wait this occasion. We also want to say how proud we’re of our members’ participation and the way grateful we are for his or her generous support,” said invoice horner, senior vice president/leader actual estate officer at los angeles health.

The occasion is open to the public for a minimum donation of $20 in assist of augie’s quest. For details on the event or a way to make a donation, go to unique web page.

About l. a. health

A. fitness is one of the fastest growing fitness center chains inside the u.s. and presently has more than 690 places in 32 states and canada. Its project is to help as many people as feasible gain the advantages of a wholesome way of life by means of creating a national community of fitness golf equipment, providing its participants the widest variety of facilities and the friendliest carrier at an low cost charge.

Approximately augie’s quest

Augie nieto created augie’s quest following his prognosis of als in march 2005. Nieto is co-founder and previous president of life health of chicago, and chairman of octane health. Augie’s quest without delay finances the als remedy improvement institute (als tdi), the sector’s predominant drug discovery middle centered entirely on locating a cure for als. For extra information on augie’s quest and to get concerned, go to unique page.

26
Oct

CRF Grants Support the Quest for a Cure

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The cystinosis studies foundation is the largest issuer of grants for cystinosis studies. whilst we are saying biggest we don’t mean within the united states, we suggest in the global. in fact, final yr the crf provided a total of $2.79 million really worth of research offers in 5 exceptional international locations. this cash funded seventeen clinical research concerning the pathology, remedy, and capacity treatment options for cystinosis.

Please discover the entire press release by using the cystinosis studies foundation below.

Cystinosis is a unprecedented, incurable metabolic disorder that afflicts 500 children and young adults inside the america and about 2,000 humans international. It slowly destroys the organs in the frame (consisting of the kidneys, liver, eyes, muscle tissues and mind) because of a buildup of the amino acid cystine that crystallizes and kills the cells.

The 2016 offers, funded by way of donations from the 2016 natalie’s want gala and golfing tournament and donations from cystinosis own family occasions throughout the yr, are supporting studies inside the united states of america, belgium, france, italy and new zealand. they include:

Nine cell and molecular studies into the pathogenesis of the sickness

2 stem cellular/gene remedy research

Five research into new drug discoveries

1 neurological research take a look at

Crf-funded research has brought about new discoveries approximately the pathogenesis of cystinosis and has helped unlock the mysteries of this uncommon ailment. The muse anticipates that there will be fda approval this year for clinical trials to improve an autologous stem mobile treatment and the development of a nanowafer treatment for corneal cystinosis.

“A number of the research performed by way of crf funded scientists has far-accomplishing implications for other issues.” stated crf founder nancy stack.  “Despite the fact that the cystinosis network is small, knowledge found by using analyzing our disorder has led to advancements inside the discovery of ability treatments for other sicknesses such as huntington’s disorder, parkinson’s disorder and other systemic problems similar to cystinosis.

“Our work inside the vicinity of nanotechnology and corneal cystinosis will undoubtedly assist other corneal sicknesses. the stem cellular paintings performed through stéphanie cherqui, ph.d., (united states) will help treat other lysosomal or even neuro-muscular degenerative disorders. crf research extends some distance past our network; it has the capability to treat thousands and thousands of different folks that be afflicted by different disorders.”

For the reason that 2003, the cystinosis research basis has issued 151 cystinosis studies grants in 12 international locations. amongst other improvements in the take a look at of the disease, crf funded the development of not on time-release cysteamine medicine, accepted in 2013 by the u.s. meals and drug management.

Donations made to crf cross directly to fund cystinosis research.

This year’s research supply awards consist of:

U.S.

The scripps research institute, la jolla, california

$256,795, to sergio catz, ph.d., “molecular trafficking regulators of dynamic organelles in cystinosis”

$Seventy five,000 to sergio catz, ph.d., and jinzhong zhang, ph.d., “improvement of cell function thru chaperone-mediated autophagy and cell trafficking in cystinosis”

College of california, san diego, california

$A hundred and sixty,589 to ilya gertsman, ph.d., and bruce barshop, m.d., ph.d, “elucidation of altered metabolism and biomarkers in cystinosis the usage of huge-scale metabolomics processes”

$141,082 to stephanie cherqui, ph.d., “improved research software for stem cell research

$Sixty two,895 to doris trauner, m.d.,“sleep disturbance and reminiscence function in nephropathic cystinosis”

Thiogenesis therapeutics, inc., san diego, california

$153,900 to vincent stanton, jr., m.d., and patrice rioux, m.d., ph.d., “pharmacokinetic assessment and optimization of cysteamine precursors”

Harvard medical faculty, Boston, Massachusetts

$225,000 to norbert perrimon, ph.d., and patrick jouandin, ph.d., “profiling metabolic dysfunction because of cystinosis.”

Massachusetts fashionable medical institution, Boston, Massachusetts

$ninety six,129 to florian eichler, m.d., and sherman alexander, m.s.c., “scientific trial readiness for distal myopathy in nephropathic cystinosis (dmnc)”

College of pittsburgh school of drugs, pittsburgh, pennsylvania

$A hundred and fifty five,484 to morgan fedorchak, ph.d., and kanwal nischal, m.d., frco, “development of a topical, controlled release cysteamine eye drop”

Belgium

De duve institute, Brussels

$209,344, to pierre courtoy, m.d., ph.d., and christopher pierreux, ph.d., “assessment of ctns -/- mice protection by means of oral supplementation with basic amino-acids: focus on kidneys”

France

Imagine institute, paris, france

$310,000, to corrine antignac, m.d., ph.d., “characterization of mtorc1 signaling in early pathogenesis of cystinosis”

$Ninety one,553 to matias simons, m.d., “lessons from the fruit fly. how cells deal with cystinosin deficiency.”

Paris descartes university, France

$225,000 (a 3-yr supply) to bruno gasnier, ph.d., and yann terres, m.s.c, “mechanism and pathophysiological significances of a genetic interaction of cystinosin”

$Seventy five,000 to bruno gasnier, ph.d., and rossella conti, ph.d., “biophysical observe of cystinosin and pqlc2”

Italy

Bambino gesù kids’s health facility, Rome, Italy

$229,660 to francesco emma, m.d., and laura rega, ph.d., “alternative therapies for nephropathic cystinosis”

$One hundred eighty,400 to giusi pencipe, ph.d., and fabrizio de benedetti, m.d., ph.d., “nlrp2 in the pathogenesis of cystinosis.”

New zealand

The college of auckland, new zealand

$One hundred forty five,852 to alan davidson, ph.d., and teresa holm, m.d., ph.d., “kidney organoids: a brand new model to examine cystinosis.”

Approximately the cystinosis studies basis

The cystinosis studies foundation is devoted to locating better remedies to improve the pleasant of lifestyles for people with cystinosis and to ultimately discover a treatment for this devastating ailment. seeing that 2003, it has raised and devoted extra than $35 million to support bench, scientific and translational studies to find better treatments and a treatment for cystinosis. the muse is dedicated to educating the public and clinical network about cystinosis to ensure early analysis and proper treatment.

26
Oct

Quest for a Cure 2017

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The 8th annual quest for a therapy walkathon will be held sunday, september 24, 2017 at vfw park in royal oak, michigan. This event is organized with the aid of 9 metro detroit-place households on behalf of their kids with rett syndrome: the cardinalis (giavanna), the casses (ashton), the macdonalds (annie), the petersons (jillian), the pettys (hailey), the rokickis (olivia), the scappaticcis (isabella), the weinrauchs (emily), and the zerials (mia).

Even as we actually inspire anyone to attend the walkathon – it’s always a top notch day for the entire family with correct meals, true amusing, and notable raffle prizes – we are hoping even people who cannot make it’s going to recall creating a donation in help of our occasion! For more records at the event and the way to participate, click on right here to go to the internet site.

26
Oct

Q’wemtsin Quest for a Cure

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1 in eight canadian girls will develop breast most cancers in their lifetime. allow’s promise to trade that.

We’re participating on this year’s canadian most cancers society cibc run for the therapy to benefit the breast most cancers motive. we’re jogging in honour of all the amazing girls in our lives, and we want your assist!

Please contribute what you can to our fundraising. each dollar makes a difference and gets us one step closer to making breast cancer beatable. your donation will fund innovative studies to help keep the lives of more girls, and provide help packages to those stricken by this sickness.

Did you realize that just $a hundred ought to fund 2 hours of lifesaving research in a global magnificence laboratory? your contribution lead to the subsequent leap forward!

Together, we are able to exchange the destiny of breast most cancers.

Make donation

10
Oct

The Final Roster

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Since the inception of the Quest for the Cure, we have seen a number of roster changes, for reasons ranging from personal to professional to health-related. It has been a long road – no pun intended – and when we bought our tickets last week, we had our final roster in mind.

On September 27th, Dan and Drew will be boarding a flight to Belfast.

This final roster change – bringing us to just two Wayfarers making the trip – does mean a few things will be changing. First and foremost, we won’t be able to hold watches; doing so while also trying to sleep enough for our physical activity levels is just impractical.

We will also be carrying the gear ourselves, but that might not make much of a change – we’ll have less gear to carry, simply because we have fewer people in tents, fewer people eating food, so on and so forth. We’ll still have to carry all of our cooking gear between the two of us, but we can be more selective about what we bring even for that.

To answer a few questions we’ve gotten, though:

Yes, our goal is still $100,000. We are not lowering our fundraising goal, and with your help – everyone reading this – I am confident that we can still reach it.

No, there is no chance that we will cancel the trip. No chance at all. We are committed – and not only because those plane tickets are non-refundable!

We leave Toronto on September 27th, and return on October 28th. We’ll be walking for about 24 of the days in between there, taking a few days off here and there to recuperate and rest our legs. A more detailed itinerary will be posted closer to our flight, I promise – we want anyone in the area to come out and say hello!

What was once akin to the Fellowship has come down to just a pair of guys making their way, but that didn’t stop Frodo and Sam and it won’t stop us.

10
Oct

A New Site

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Longtime readers will notice that we haven’t had many updates lately, but I am glad to say that this is about to change.

In the coming weeks we are finally pulling all of the loose threads of a master plan together and publishing our press package for the Wayfarers’ summer campaign leading up to our walk. Part of that is a refurbished website, and that means new content, exciting announcements, and even a ‘vlog that will be published as often as our poor NPC Brittany is able to piece clips of boring walks together.

Our refurbished website is going to be followed by a social media campaign that will see us more active on Facebook, Twitter, Google + and even YouTube and Tumblr in the near future.

This is our inaugural post using our “Facebook-integrated” website, a first (public) step in the new website. Please check out the features we have now – from Facebook comments to easy sharing with your friends! Help us spread the word and get to our goal!

10
Oct

Buy our wristbands!

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Paul posted about our Wayfarers: Quest for the Cure silicone bracelets a few weeks back, but as of yesterday we are able to send them anywhere in the United States for a small fee.

On our friend (and NPC) Jenn Syas’ etsy page, you can buy the wristbands for the same price we are selling them in person using any major credit card. A shipping charge of just $2 will be added if you can’t receive the wristband in person.

As Paul posted in his original message, $4 from each wristband sale will go directly to the cancer society for the region in which you live (if you’re in Canada, it will be the Canadian Cancer Society; if you’re in America, it will be the American Cancer Society; anywhere else will be donated to the Association for International Cancer Research). The other $1 will help us recoup expenses for the wristbands, as well as a small amount towards our business cards.

We have already sold a couple dozen of these wristbands but have literally hundreds more to sell – buy one (or several!) and show your support today! Click here to go directly to the Etsy page!

10
Oct

Contest winners and a new one on the horizon!

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It’s taken us some time, but we have finally recovered from our fantastic Burns Night at the Dukelast week. In the wake of this we can finally announce the winners of the contest that ended in mid-December… and announce a new one that’s starting today!

After narrowing down the entrants, we settled on a tagline that’s been used on the site since the beginning of this year:

Walking in the footsteps of history for a brighter future.

We believe that it speaks to our mission statement and our methods in a way none of the other entries quite hit. We did have a lot of great entries, however, and thank you to everyone who sent one our way. David Syas of Nashua, New Hampshire, who entered this tagline, has generously donated his prize back to the Wayfarers. His name has been put on our list of donors and the $40 has been donated directly to his home charity, the American Cancer Society.

The runner up, “the journey to end cancer starts with a single step,” was suggested by Pat Scanlon of Rochester, New York, whose t-shirt is ready to be delivered to him!

The visual advertisement we chose wasn’t quite perfect – we got a number of entries that we liked (I am wearing one right now, in t-shirt form, that was the runner-up), but the one we all chose was an early version of the following. We had the winner, Florida native Kelly Lee, do a few minor changes before sending us the following:

You can download wallpapers (1024×713; 800×600; 640×480) if you like. Kelly’s prize has already been sent.

The runner-up image, submitted by Alexandra Misset of our hometown Toronto, was actually a t-shirt design. We ordered some of these shirts for the Wayfarers’ training this summer and I’ve been wearing my two new hoodie sweatshirts everywhere – I’ll get some pictures soon and post them up.

A New Contest

Starting today, we are holding a contest that hearkens back to the reason we all love high fantasy to begin with: stories.

From now until the end of May – yes, that’s four months! – we are looking for submissions of short fiction, up to 5000 words in length, with a theme of “quests.” There is no genre or formatting requirement beyond that; just make sure it’s about a quest of some sort. Each entry into the contest will cost $5.

Why the cost? Because the winner of this contest will be winning 30% of the total entry fees. Second place will win 15%. Third place will win 10%. All three will get their fiction linked to on our site, as well as a link to their personal websites if they have them. And the remaining 45% will be donated directly to the Wayfarers’ charity in your region – that’s $2.25 per entry towards our cause, and a chance to win big for your writing!

Entries will be judged by a neutral panel of judges that is yet to be determined – we have some big things in the works on that front, so stay tuned for an update next week (including details on how to submit!) and start your writing.

10
Oct

Burns Night Approacheth

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When I started bouncing the idea for the Wayfarers around in my head – and in the heads of my friends – I knew that it would be a lot of work.  At first the work involved was simply training and getting gear together; then it expanded to getting the word out and trying to raise funds.

Since then it has exploded to nearly monthly events, starting with this month’s Burns Night on January 23rd.  As already briefly discussed, our Burns Night at the Duke will be a $60 plate event that will include live music, delicious served food and a chance to meet the Wayfarers and talk to us about what we are doing.

We have finally put together the Burns Night Order Form – a simple sheet that you can print off to give to a Wayfarer with cash (if you know us personally) or email details from to us.  Remember that we need a choice made for each of the options at the bottom of the sheet, for every person that is attending.

Accepting anything other than cash payments ends up costing us money; we are willing to do it via PayPal but need to charge an additional $3 (for a total of $63 per ticket) in order to cover our own costs and not take away from the fundraising that we are performing.  If you would like to attend but will not be able to pay cash until the event itself, email us and tell us so.  We will reserve your seat.

That said there are still seats available and we would love to have you for a night of great food from the Duke itself, live music provided by the York Celtic Ensemble and a cause for the ages.

Order your tickets now by emailing us here!